Impact of surface-area-to-volume ratio, internal viscosity and membrane viscoelasticity on red blood cell deformability measured in isotonic condition
نویسندگان
چکیده
منابع مشابه
Alterations in cell surface area and deformability of individual human red blood cells in stored blood
The functionality and viability of stored human red blood cells (RBCs) is an important clinical issue in transfusion. To systematically investigate changes in stored whole blood, the hematological properties of individual RBCs were quantified in blood samples stored for various periods with and without a preservation solution called CPDA-1. With 3-D quantitative phase imaging techniques, the op...
متن کاملeffect of hyperglycemic condition on observed surface area to volume ratio of human cancerous cells
the human blood basal glucose level is a completely controlled range. information on the relationship between culture glucose concentration and changes in the cell's surface area, volume and surface area to volume (s/v) ratio are lacking. cancerous epithelial-like cell lines sw480, sw742 and t-47d were cultured in mediums nourished with 4.7 mm per liter of glucose as the control group and three...
متن کاملInfluence of deformability of human red cells upon blood viscosity.
The viscosity of blood at high rates of shear is unusually low compared to other suspensions of similar concentration. The underlying mechanisms were studied by rotational viscometry, red cell filtration, viscometry of packed cells and direct microscopic observation of red cells under flow in a transparent cone plate viscometer. Deformability of red cells was altered osmotically or abolished by...
متن کاملMeasuring cell surface area and deformability of individual human red blood cells over blood storage using quantitative phase imaging
The functionality and viability of stored human red blood cells (RBCs) is an important clinical issue in transfusions. To systematically investigate changes in stored whole blood, the hematological properties of individual RBCs were quantified in blood samples stored for various periods with and without a preservation solution called citrate phosphate dextrose adenine-1 (CPDA-1). With 3-D quant...
متن کاملRed cell membrane deformability: new data.
Red cells arrested by fine fibers and subjected to drag forces in a moving stream of fluid can be stressed beyond the point of rupture. The technique, which is basically an in vitro analogue of the microangiopathic hemolytic state, thus permits a study of red cell behavior over the entire range of stress that the membrane can withstand. Measurements made by this approach show an exponential rel...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-43200-y